Set a new standard of care

First, a major difference is the lack of ionizing radiation with the Prenuvo scan (or MRI in general for that matter), as opposed to PET/CT which involves significant radiation-dosing. Therefore while in cases of already diagnosed cancer PET-CT is likely the preferred standard for initial systemic staging and treatment-response monitoring in most clinical settings, it is not a reasonable candidate modality for general screening because over the long-term, additive exposure to ionizing-radiation actually increases the risk of inducing cancer down the line. PET-CT is a very useful cancer-imaging technique because it reflects metabolic activity, which in cancer is characteristically increased relative to background normal tissue, and can do so over large anatomic coverage with cross-sectional anatomic-precision. With Prenuvo’s MRI technique, we take advantage of a functional-equivalent of PET, however capitalizing on a different physiologic principle. Just like cancer tends to be hypermetabolic relative to background normal tissue, it also tends to have relatively more cellular-density which results in relative "diffusion restriction of water molecules" which is actually very well-imaged via MRI but technically difficult to perform well over the whole-body. To this end, we have fine-tuned performance of whole-body Diffusion-Weighted-Imaging (or WB-DWI), which is a fundamental component of our Prenuvo multiparametric WB-MRI screening protocol and therefore further strengthens the degree of sensitivity and specificity our WB-MRI screening approach. In the end, to some degree WB-MRI may eventually have a degree of overlapping roles and complimentary/different contextual strengths for cancer-imaging, depending on the clinical situation. However, in the specific context of general cancer screening, WB-MRI is a more viable option due to the lack of ionizing radiation involved compared to PET-CT.

We perform a comprehensive set of protocols that image the entire body. These include brain quantification, arterial assessment, fat quantification as well as dedicated cancer and spinal screening. Our custom tailored whole body MRI protocol is based on MRI tissue-contrasts based on T1-weighted, T2-weighted, Fat-suppressed and non-fat-suppressed, and DWI techniques, a combination of evidence-based and emerging technologies that offer the most comprehensive diagnostic imaging in a reasonable time frame.

A Radiologist (physician specially trained in MRI and other radiology examinations, such as X-ray, CT and ultrasound). Our radiologists are fully licensed in the states they read in, and are or specially trained in whole body MRI screening.

No. The Prenuvo scan should not be considered as a replacement to any standard clinical guidelines-based targeted screening practices for specific types of cancer or other health conditions.