Prenuvo Signature
A clinical consultancy built around one patient at a time.
Prenuvo Signature is for a limited number of people who want a personalised, evidence-informed plan for their health, a board-certified physician experienced in interpreting and projecting health risks based on the full Prenuvo ecosystem who knows them, and can navigate them through the most current proactive screening protocols Prenuvo has developed. It is available by application.
Why personalised attention matters
Because no two bodies are the same.
We are born with different familial risk. We carry different lifestyles, different histories of injury or illness, different occupational exposures, different baseline biology. The kind of medicine that treats all of us as variations on an average will, by definition, miss the things that make us individuals. It is a serviceable model for keeping a population alive and a laudable “minimum bar” for preventative medicine. But it is not the optimal model for helping any one individual thrive.
Prenuvo Signature exists for people who think about their health that way — as something that does not stop at not-being-sick, but begins there. Living well, living long, living awake to the years you have. The plan we build for you reflects who you actually are: your natural risks, your lifestyle, your history, your goals, and the trade-offs you are willing to make.
A Prenuvo Executive membership provides a detailed structural and functional screening that benefits individuals interested in a deeper understanding of their health. Signature, which includes Executive Screening, is what happens when that screening becomes the starting point for a year-round practice of personalized proactive healthcare.
Your Signature physician
Yours.
They know your history. They know your Prenuvo results. They know what you are working on, what you are watching, and what you are choosing not to chase. They are there to support you. Responsive. Informed.
This is not a triage relationship. It is an evolved proactive physician relationship built around continuity, judgement, and time.
The single most useful clinical tool I have is continuity — having met with the same patient three or more times, I can build a relationship built on anticipation and prioritization of goals.
Preventative Medicine
The rhythm
Signature is not a series of appointments. It is a continuous practice — structured around your biology, your goals, and the rhythm that keeps you accountable to both.
Baseline and re-baseline
Your Executive imaging and detailed blood biomarkers are your periodic benchmark. All the lifestyle modification and other longevity interventions you have worked on culminate in this moment where we measure your performance and trajectory. Included annually, available more frequently if you desire. Your physician may also recommend optional specialist diagnostics (extra charges would apply) — cardiopulmonary, neurocognitive, hormonal — to help build the complete picture.
The deepdive
An unhurried after-baseline deepdive into your personal context — your medical history, your family history, your lifestyle, and your goals — and the state of your health. We agree what we are working on this year and what we are watching.
The plan
You leave with a written personal plan focused on optimization and risk reduction: interventions, lifestyle adjustments, supplements or medications where evidence supports them, a calendar for the year, and the metrics by which we will know it is working.
Periodic review
On a quarterly basis, or more if required, we check in against the plan and adjust based on what has been learned. This is the loop most medicine is missing.
Early access
Our research and engineering teams continually develop new capabilities — new scan sequences, new biomarker panels, new imaging-derived measurements, new partnerships for adjunct diagnostics. Some of these eventually become part of our standard memberships. Many of them begin, by design, inside Signature.
Signature patients are the first to receive new imaging sequences as they mature, the first to be offered new biomarker measurements as they validate, and the first to access new adjunct diagnostics as we onboard them. With your consent, your longitudinal data also feeds back into our research — which is what makes the next generation of these tools better for everyone who comes after.
You are not a beta tester.
You are the cohort that the most thoughtful parts of medicine are built around first.
From inquiry to the review of the report of the scan the folks and the process were very caring and professional. I felt quite safe and comfortable at their clinic. I have and continue to recommend this to my friends and family.
Evidence Informed Longevity Planning
The longevity space is full of claims, and not all of them are equally supported. Your dedicated physician can help separate evidence from marketing, explain what is known and unknown, and help you understand which topics may be relevant to your health goals, imaging findings, biomarkers, and broader clinical context.
Heart Health & CAD Risk Reduction
Using insights from your AI advanced heart scans, wb-MRI, and deep lipid biomarkers, we project your cardiovascular risk. Where appropriate, we augment lifestyle interventions with thoughtful medical guidance to help reduce coronary artery disease (CAD) risk.
Metabolic Health
Metabolic health is the cornerstone of longevity. We identify risks of insulin resistance, track your glycemic markers and may advise a variety of treatments to reverse insulin resistance, stabilize blood sugar, and optimize your metabolic lifespan.
Body Composition
Relying on Body Composition Analysis and metabolic labs, we design comprehensive plans to shed visceral fat and build lean muscle mass along with analysis of targeted weight-loss medications, supplements, and strength-training modifications.
Hormonal Health & HRT
We provide safe, evidence-informed guidance for Thyroid optimization, Menopausal symptom relief, and Men’s Testosterone Hormone Replacement Therapy (HRT). Your Prenuvo physician will explain the evidence, potential risks, and monitoring needs to safely balance your hormones.
Your Prenuvo physician will not chase trends, will not recommend what is not evidence informed, and will provide clear safeguard guidance for treatments you may pursue. They will explain what the evidence and intention is for any intervention they recommend, and help you connect with expert clinicians that may be helpful in starting or managing advanced treatment solutions. That is the difference between a wellness offering and a medical one.
Who Signature is and is NOT for
Signature is for people who
Are ready for a health optimization and advanced longevity consultant to build off their existing foundation with a primary care provider.
Want a personalised, evidence-informed health plan and the time of a physician who knows them.
Value both continuity of care and convenience.
Are willing to participate in their own plan — to do the things the plan calls for.
Want first access to the most current proactive medicine Prenuvo has.
Signature is not for people who
Are trying to replace their Primary Care Provider, address acute symptom or have emergency care needs.
Want a transactional relationship.
Are looking for interventions that are not evidence-informed — that is not the practice we run. This does not mean we cannot be cutting edge.
Want their physician to make every decision for them — we build plans with you, not for you.
Early access
Our research and engineering teams continually develop new capabilities — new scan sequences, new biomarker panels, new imaging-derived measurements, new partnerships for adjunct diagnostics. Some of these eventually become part of our standard memberships. Many of them begin, by design, inside Signature.
Signature patients are the first to receive new imaging sequences as they mature, the first to be offered new biomarker measurements as they validate, and the first to access new adjunct diagnostics as we onboard them. With your consent, your longitudinal data also feeds back into our research — which is what makes the next generation of these tools better for everyone who comes after.
You are not a beta tester.
You are the cohort that the most thoughtful parts of medicine are built around first.
From inquiry to the review of the report of the scan the folks and the process were very caring and professional. I felt quite safe and comfortable at their clinic. I have and continue to recommend this to my friends and family.